ANALYSIS OF ANTIMICROBIAL RESISTANCE IN PATIENTS WITH BACTERIAL MENINGITIS AT A HOSPITAL IN THE EXTREME SOUTH OF SANTA CATARINA

Authors

  • Mariângela Mendes Recco UNESC
  • Natasha Guglielmi dos Santos UNESC
  • Guilherme Bianchini

DOI:

https://doi.org/10.18616/inova.v16i2.9155

Abstract

ABSTRACT

 

Meningitis is defined as an inflammation of the meninges, it is an inflammatory process in the cerebrospinal fluid (CSF). Bacterial meningitis is caused by bacterial invasion into the CSF; The most common bacteria are Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae and in neonates, Streptococcus agalactiae. The most common entry points are through the respiratory tract and droplets from the nose and throat. The mechanism of action begins with colonization of the nasopharynx, followed by bacteremia and entry into the central nervous system (CNS). Diagnosis can be made by CSF culture, polymerase chain (PCR) evidence, latex agglutination, direct bacterioscopy and chemocytological examination of the CSF. Resistance to bacteria is characteristic of resistant genes that are passed on to other cells. To carry out resistance analysis, the antibiogram is used. The objective of the study was to evaluate antibiotic resistance through antibiograms of patients at a hospital located in the extreme south of Santa Catarina. It was a cross-sectional observational study that used medical records from January 2014 to December 2023 from a hospital database. As a result, the most used antibiotic was Ceftriaxone, the one with the greatest resistance was Erythromycin and is supplied by the most prevalent coagulase-negative Staphylococcus bacteria.


Keywords: Bacterial meningitis. Resistance. Antibiogram.

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Published

2026-06-30

Issue

Section

Atenção à Saúde